f you’re anything like me, you’ve spent a lot of time wondering why some people are naturally very muscular and others aren’t. Obviously, diet and lifestyle play a role but there is no denying the fact that there is also a major genetic component. Myostatin, a type of myokine protein is the main genetic component that regulates muscle growth potential. Genetically gifted bodybuilders have very low levels of myostatin in their bodies. Experiments where animals were born without myostatin grew muscle endlessly with little exercise.
A number of supplements have been designed to inhibit myostatin production over the past 20 years, but none of them have been very effective – until now.
Epicatechin is a bioactive flavanol found in trace amounts in green tea and cocoa. Research with epicatechin indicates that it increases levels of follistatin, a unique type of protein found in the muscle cells which binds to and inhibits the actions of myostatin in the body. Epicatechin increases follistatin and more follistatin equals less myostatin, which in turn means more muscle.
Animals lacking myostatin, either due to a defective gene or because they’ve been treated with compounds that inhibit production, show huge increases in muscularity. The limits of muscle growth are removed by the inhibition of myostatin.
Clinical studies with epicatechin show multiple physiological benefits, including:
- Enhanced muscle growth and strength
- Increased nitric oxide production-improving vascularity, blood flow and endurance
- Improved muscle insulin sensitivity
- Lowered total cholesterol levels
- Improved brain and heart health
Whether you’re looking to build muscle, burn fat or increase athletic performance, epicatechin is a worthwhile addition to your supplement arsenal, and because it’s non-hormonal, epicatechin can be used by both men and women with no side effects.
A clinical trial where older adults were given 50mg of epicatechin per day found that the follistatin/myostatin ratio increased 49% after only 7 days of supplementation. Another clinical trial found that 200mg of epicatechin per day improved endurance and prevented muscular fatigue by inhibiting the aerobic and mitochondrial succinate dehydrogenase adaptations that occur during exercise.
Animal studies support these finds. Epicatechin given to mice decreased myostatin by 18% and increased follistatin by 56%.
New research is looking at epicatechin as a way to prevent sarcopenia, a loss of muscle associated with age. In elderly human subjects, levels of myostatin decreased 28%, while follistatin increased 30% after only 7 days of treatment with epicatechin. Treatment with epicatechin also yielded a 7% increase in muscular strength.
Clinical research shows that a dosage of only 50mg/day is necessary to see results, but empirical usage suggests that epicatechin should be dosed at 1-2mg/kg of bodyweight. Feedback from users suggests that dosing at the higher end, around 250mg per day, is optimal to maximize the athletic and muscle building benefits.
The Bottom Line
Myostatin is the main genetic component that regulates muscle growth potential. Epicatechin is a bioactive flavanol that increases follistatin. More follistatin equals less myostatin, and less myostatin means more muscle. Epicatechin will make any other muscle building ingredients you stack with it more effective. You can stack epicatechin with natural muscle building ingredients like arachidonic acid and laxogenin.
Each capsule of Enhanced Labs EPIMUSCLE contains 250mg of pure Epicatechin.
As a dietary supplement, take 2 capsules daily or as directed by your physician.
This product is only intended to be consumed by healthy individuals 18 years of age or older. Consult your physician prior to use if you are pregnant or nursing. Do not exceed recommended use. Imporper use will not improve results and is not advised. Keep out of reach of children. Store in a cool dry place. Do not use if safety seal is broken.
THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.